PPP Platform

PK/PD Simulation
Clinical Trial Design

Virus Selection

Virus Family

Virus Name

Drug and Pharmacokinetic Parameters

Drug 1

Drug Selection

Using Model Library

Route of Administration

Clearance (L/h):

Protein Binding (%):

Volume of Distributions (L):

Target Sites

Patient Settings

Body Weight (kg):

Treatment

Treatment 1

Dosing per Body Weight

Dosing Drug

Duration (day):

Delay (day):

Maintenance Dose (mg/kg):

Dosing Interval (h):

Infusion Duration (min):

Pharmacodynamics

Evaluation Method

In-vitro EC50 (mg/L):

Sample Size Estimation

Viral Dynamics Endpoint Selection

Control Group Selection

Treatment Group Selection

Test Selection

Allocation Ratio:

Control Group

Treatment Group

Power (%)

Significance Level (%)

Power Analysis

Viral Dynamics Endpoint Selection

Control Group Selection

Treatment Group Selection

Test Selection

Allocated Sample Size:

Control Group

Treatment Group

Significance Level (%)

Total Number of Simulations

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Summary
Treatment 1

Pharmacokinetics